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Aplidin, plitidepsin, as PM90001 | PharmaMar
Aplidin, plitidepsin, as PM90001 | PharmaMar

Aplidin in patients with advanced dedifferentiated liposarcomas: a French  Sarcoma Group Single-Arm Phase II study - Annals of Oncology
Aplidin in patients with advanced dedifferentiated liposarcomas: a French Sarcoma Group Single-Arm Phase II study - Annals of Oncology

Aplidin™ induces the mitochondrial apoptotic pathway via oxidative  stress-mediated JNK and p38 activation and protein kinase C δ | Oncogene
Aplidin™ induces the mitochondrial apoptotic pathway via oxidative stress-mediated JNK and p38 activation and protein kinase C δ | Oncogene

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting  the host protein eEF1A
Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

Of 72 antivirals tested in the laboratory, plitidepsin proves to be the  most effective in preventing SARS-CoV-2 replication | IrsiCaixa
Of 72 antivirals tested in the laboratory, plitidepsin proves to be the most effective in preventing SARS-CoV-2 replication | IrsiCaixa

New drugs and novel mechanisms of action in multiple myeloma in 2013: a  report from the International Myeloma Working Group (IMWG) | Leukemia
New drugs and novel mechanisms of action in multiple myeloma in 2013: a report from the International Myeloma Working Group (IMWG) | Leukemia

Establishment and characterisation of a human carcinoma cell line with  acquired resistance to Aplidin™ | British Journal of Cancer
Establishment and characterisation of a human carcinoma cell line with acquired resistance to Aplidin™ | British Journal of Cancer

Plitidepsin (Aplidin) targets tumor-associated Nurse-Like cells (NLCs)....  | Download Scientific Diagram
Plitidepsin (Aplidin) targets tumor-associated Nurse-Like cells (NLCs).... | Download Scientific Diagram

Plitidepsin: a potential new treatment for relapsed/refractory multiple  myeloma | Future Oncology
Plitidepsin: a potential new treatment for relapsed/refractory multiple myeloma | Future Oncology

Marine Drugs | Free Full-Text | Antitumor Peptides from Marine Organisms |  HTML
Marine Drugs | Free Full-Text | Antitumor Peptides from Marine Organisms | HTML

Molecules | Free Full-Text | Approaches to the Potential Therapy of  COVID-19: A General Overview from the Medicinal Chemistry Perspective | HTML
Molecules | Free Full-Text | Approaches to the Potential Therapy of COVID-19: A General Overview from the Medicinal Chemistry Perspective | HTML

Phamamar achieve to extend the comercialization of its marine derived anti  cancer drugs over eleven latinamerican countries.
Phamamar achieve to extend the comercialization of its marine derived anti cancer drugs over eleven latinamerican countries.

Plitidepsin: design, development, and potential place in therapy | DDDT
Plitidepsin: design, development, and potential place in therapy | DDDT

Oxidation and inactivation of low molecular weight protein tyrosine  phosphatase by the anticancer drug Aplidin - Taddei - 2006 - International  Journal of Cancer - Wiley Online Library
Oxidation and inactivation of low molecular weight protein tyrosine phosphatase by the anticancer drug Aplidin - Taddei - 2006 - International Journal of Cancer - Wiley Online Library

Plitidepsin: design, development, and potential place in therapy | DDDT
Plitidepsin: design, development, and potential place in therapy | DDDT

Dehydrodidemnin B - an overview | ScienceDirect Topics
Dehydrodidemnin B - an overview | ScienceDirect Topics

AplidinTM Induces Apoptosis in Human Cancer Cells via Glutathione Depletion  and Sustained Activation of the Epidermal Growth Factor Receptor, Src, JNK,  and p38 MAPK* - Journal of Biological Chemistry
AplidinTM Induces Apoptosis in Human Cancer Cells via Glutathione Depletion and Sustained Activation of the Epidermal Growth Factor Receptor, Src, JNK, and p38 MAPK* - Journal of Biological Chemistry

Oncology clinical pipeline marine inspired drugs | PharmaMar
Oncology clinical pipeline marine inspired drugs | PharmaMar

Role of Cu 2+ in Aplidin s -induced apoptosis in MDA-MB-231 cells |  Download Table
Role of Cu 2+ in Aplidin s -induced apoptosis in MDA-MB-231 cells | Download Table

Aplidin synergizes with cytosine arabinoside: functional relevance of  mitochondria in Aplidin-induced cytotoxicity | Leukemia
Aplidin synergizes with cytosine arabinoside: functional relevance of mitochondria in Aplidin-induced cytotoxicity | Leukemia

Aplidin (plitidepsin) is a novel anti-myeloma agent with potent  anti-resorptive activity mediated by direct effects on osteoclasts. -  Abstract - Europe PMC
Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts. - Abstract - Europe PMC

JPM | Free Full-Text | Plitidepsin: Mechanisms and Clinical Profile of a  Promising Antiviral Agent against COVID-19 | HTML
JPM | Free Full-Text | Plitidepsin: Mechanisms and Clinical Profile of a Promising Antiviral Agent against COVID-19 | HTML

Exploring the effect of aplidin on low molecular weight protein tyrosine  phosphatase by molecular docking and molecular dynamic simulation study -  ScienceDirect
Exploring the effect of aplidin on low molecular weight protein tyrosine phosphatase by molecular docking and molecular dynamic simulation study - ScienceDirect

Plitidepsin | C57H87N7O15 - PubChem
Plitidepsin | C57H87N7O15 - PubChem

Dehydrodidemnin B - an overview | ScienceDirect Topics
Dehydrodidemnin B - an overview | ScienceDirect Topics

New drugs in multiple myeloma: mechanisms of action and phase I/II clinical  findings - The Lancet Oncology
New drugs in multiple myeloma: mechanisms of action and phase I/II clinical findings - The Lancet Oncology